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Triamterene is primarily metabolized to the sulfate conjugate of hydroxytriamterene.
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Whenever adverse reactions are moderate to severetherapy should be reduced or withdrawn.
Triamterene and quinidine have similar fluorescence spectrathus MAXZIDEtriamterene and hydrochlorothiazidemay interfere with the measurement of quinidine.
Do not stop taking this medication without consulting your doctorSome conditions may become worse when this drug is suddenly stoppedYour dose may need to be gradually decreased.
It is important for you to keep a written list of all of the prescription and nonprescriptionover-the-countermedicines you are takingas well as any products such as vitaminsmineralsor other dietary supplementsYou should bring this list with you each time you visit a doctor or if you are admitted to a hospitalIt is also important information to carry with you in case of emergencies.
Triamterene is rapidly absorbed following oral administrationPeak plasma levels are achieved within one hour after dosingTriamterene is primarily metabolized to the sulfate conjugate of hydroxytriamtereneBoth the plasma and urine levels of this metabolite greatly exceed triamterene levels.
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